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This paper introduced a new identification method, the 2-dimensional molecular marking method (2-DM), for Chinese materia medica identification. It can be used in genuine/false discriminating and quality evaluating for the Chinese materia medica. Concept, principle and process of 2-DM method were introduced in this paper. The technical advantages and contributions of 2-DM method in the study of Chinese materia medica were also discussed. Generally speaking, the occurring of 2-DM method would not only expand connotation of identification of Chinese materia medica but provide another effective way for quality evaluating.

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