A young mountaineer suffered from sudden cardiac arrest at high altitude. Cardiopulmonary resuscitation was initiated immediately. After 30 min a rescue team arrived and successfully defibrillated ventricular fibrillation upon which spontaneous circulation returned. The subsequent ECG was suggestive of extensive anterior myocardial infarction. Therefore, the patient was thrombolysed and transferred for primary percutaneous coronary intervention. Echocardiography revealed severely reduced left ventricular function with antero-septo-apical akinesia. However, angiography showed unobstructed coronary arteries. The patient fully recovered and left ventricular function normalised within 2 weeks. It may be speculated that exposure to high altitude resulted in acute coronary thrombosis which dissolved by rapid thrombolysis.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028061 | PMC |
http://dx.doi.org/10.1136/bcr.07.2009.2130 | DOI Listing |
Int J Biol Sci
January 2025
Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Cognitive impairment caused by anesthesia and surgery is one of the most common complications with multiple etiologies that occurs in elderly patients. The underlying mechanisms are not fully understood, and there is a lack of therapeutic strategies. Increasing evidence has demonstrated that myelin loss, abnormal phosphorylation of the tau protein and neuronal apoptosis are substantial driving factors of cognitive deficits.
View Article and Find Full Text PDFBMJ Open
January 2025
School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
Objective: Physical activity (PA) has been generally recognised as beneficial for health. The effect of a change in PA on kidney biomarkers in healthy individuals without kidney disease remains unclear. This manuscript synthesised the evidence of the association of changes in PA with kidney biomarkers in the general population free from kidney disease.
View Article and Find Full Text PDFHigh Alt Med Biol
January 2025
Department of Respiratory Medicine, University Hospital Zurich, Zurich, Switzerland.
Häfliger, Alina, Aline Buergin, Laura C. Mayer, Maamed Mademilov, Mona Lichtblau, Talantbek Sooronbaev, Silvia Ulrich, Konrad E. Bloch, and Michael Furian.
View Article and Find Full Text PDFBiochim Biophys Acta Gen Subj
January 2025
RIKEN Center for Sustainable Resource Science, Yokohama 230-0045, Japan; Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan.
Background: Finger millet, a C plant with mesophyll and bundle sheath cells, has been cultivated at high altitudes in the Himalayas owing to its adaptability to stressful environments. Under environmental stresses such as high light and drought, finger millet mesophyll chloroplasts move toward the bundle sheath, a phenomenon known as aggregative arrangement.
Methods: To investigate the effect of low temperatures on mesophyll chloroplast arrangement in finger millet, we conducted microscopic observations and photochemical measurements using leaves treated at different temperatures in light or darkness, with or without pharmacological inhibitors.
J Physiol
January 2025
Cerebrovascular Health Exercise and Environmental Research Sciences Laboratory (CHEERS), Department of Exercise Science, Physical & Health Education, University of Victoria, Victoria, BC, Canada.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!