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Relationships between gonadotropins, sex hormones, and vascular structure and function in adolescents of varying weight statuses have not been fully investigated. In the present study, we examined associations among these in female and male adolescents with normal weight or obesity. We performed a cross-sectional analysis of adolescents ( = 58; 12-<18 years) grouped according to BMI percentile (BMI%) into normal weight (5th-<85th BMI%; = 25) and obesity (≥95th BMI%; = 33) categories.

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Article Synopsis
  • The study assesses a 10-week web-based healthy lifestyle program for children aged 7-13 with overweight/obesity, comparing outcomes to a control group.
  • Significant improvements were found in the intervention group's BMI z-scores, quality of life, dietary habits, and physical activity levels.
  • Results suggest that e-Health interventions can effectively enhance health outcomes in children with obesity, but further research is needed to understand long-term impacts and optimize program delivery.
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As the main pioneer in the field of dendrimers, a term that he coined in 1985 in reference to their tree-like structure, Prof. Donald A. Tomalia has inspired several generations of researchers worldwide [.

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Background: World Health Organization (WHO) growth standards, including weight-for-length, are used to monitor infant size. Excessive infant weight-for-length at or above the 85th percentile is a risk for childhood overweight. Although antenatal interventions like the nutrition and exercise lifestyle intervention program (NELIP) have successfully prevented excessive gestational weight gain, strategies to improve the intervention remain of interest.

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Context: Insulin sensitivity and secretion indices can be useful tools in understanding insulin homeostasis in children at risk for diabetes. There have been few studies examining the reproducibility of these measures in pediatrics.

Objective: To determine whether fasting or oral glucose tolerance test (OGTT)-derived insulin measures would be more reproducible and whether there would be differences based on weight, sex, race, and pubertal status.

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