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Perianal cutaneous malakoplakia in a patient with anti-MDA5 dermatomyositis.
J Dermatol
January 2025
Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.
Primary cutaneous malakoplakia of the medial thigh in an 81-year-old immunocompetent patient.
JAAD Case Rep
August 2024
SkinPath Solutions, Smyrna, Georgia.
Malakoplakia Involving the Maxilla: A Case Report and a Review of the Literature.
Head Neck Pathol
June 2024
Division of Dental and Oral Medicine, New York-Presbyterian/Queens, Flushing, New York, USA.
Article Synopsis
- Malakoplakia is a rare inflammatory disorder mainly seen in immunocompromised patients, characterized by an inability of macrophages to effectively kill bacteria.
- Although it usually occurs in the genitourinary and gastrointestinal regions, this report highlights a rare case where malakoplakia affected the maxilla and maxillary alveolar ridge mucosa, marking a unique instance of oral cavity involvement.
- Diagnostic stains revealed specific patterns indicating malakoplakia without evidence of microbial infection, emphasizing the need for clinicians and pathologists to consider this condition when evaluating lesions in immunosuppressed patients.
Ovarian tumour-cutaneous fistula as a primary presentation of pelvic malakoplakia coexisting with a benign ovarian tumour mimicking advanced ovarian cancer.
BMJ Case Rep
June 2024
Obstetrics and Gynaecology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Article Synopsis
- Malakoplakia is a rare disease that causes chronic inflammation, usually in the urogenital organs, and can be diagnosed by looking for special bodies called Michaelis-Gutmann bodies.
- In this case, a patient was wrongly diagnosed with advanced ovarian cancer but actually had malakoplakia along with an ovarian tumor that created a connection to her skin.
- After surgery to remove the problematic tissue, she took antibiotics for six months and showed no signs of the disease coming back after two years.
A very complicated UTI: malakoplakia following E. coli urinary tract infection.
BMC Nephrol
June 2024
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Malakoplakia is a rare inflammatory disorder believed to result from a defect in macrophage phagocytic function triggering a granulomatous reaction. It can present with genitourinary, gastrointestinal, or cutaneous manifestations in immunocompromised or, less commonly, immunocompetent hosts. We describe a case of renal malakoplakia in a young, otherwise healthy patient presenting with nephromegaly and sepsis following an E.
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