The aim of this study was to predict stress modification in the temporomandibular joint (TMJ) after symphyseal distraction (SD). The study was performed using three-dimensional finite element analysis using a complete mastication model. Geometric data were obtained from MRI and CT scans of a healthy male patient and each component was meshed as various regions. The distraction was performed with a 10mm expansion after simulation of a surgical vertical osteotomy line on the model in the mandibular midline region. The geometry and mesh of the bone callus were constructed. The bone callus was modelled as a strengthened region characterized by a Young's modulus corresponding to consolidated bone to predict the long-term biomechanical effect of SD. Boundary conditions for jaw closing simulations were represented by different jaw muscle load directions. The von Mises stress distributions in both joint discs and condyles during closing conditions were analysed and compared before and after SD. Stress distribution was similar in discs and on condylar surfaces in the pre- and post-distraction models. The outcomes of this study suggest that anatomical changes in TMJ structures should not predispose to long-term tissue fatigue and demonstrate the absence of clinical permanent TMJ symptoms after SD.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijom.2012.06.005DOI Listing

Publication Analysis

Top Keywords

stress distribution
8
temporomandibular joint
8
jaw closing
8
symphyseal distraction
8
finite element
8
bone callus
8
comparison stress
4
distribution temporomandibular
4
joint jaw
4
closing symphyseal
4

Similar Publications

FhaA plays a key role in mycobacterial polar elongation and asymmetric growth.

mBio

January 2025

Analytical Biochemistry and Proteomics Unit, Instituto de Investigaciones Biológicas Clemente Estable and Institut Pasteur de Montevideo, Montevideo, Uruguay.

Unlabelled: Mycobacteria, including pathogens like , exhibit unique growth patterns and cell envelope structures that challenge our understanding of bacterial physiology. This study sheds light on FhaA, a conserved protein in , revealing its pivotal role in coordinating cell envelope biogenesis and asymmetric growth. The elucidation of the FhaA interactome in living mycobacterial cells reveals its participation in the protein network orchestrating cell envelope biogenesis and cell elongation/division.

View Article and Find Full Text PDF

Introduction: In order to elucidate the physiological mechanism of post-flowering assimilate transport regulating the formation of yields in arid regions and to provide technological support for further water-saving and high yields in the wheat region in Xinjiang, we conducted a study on the effects of different fertility periods and different degrees of drought and re-watering on the post-flowering dry matter accumulation and transport of spring wheat and the characteristics of grain filling.

Methods: In two spring wheat growing seasons in 2023 and 2024, a split-zone design was used, with the drought-sensitive variety Xinchun 22 (XC22) and drought-tolerant variety Xinchun 6 (XC6) as the main zones and a fully irrigated control during the reproductive period [CK, 75%~80% field capacity (FC)], with mild drought at the tillering stage (T1, 60%~65% FC), moderate drought at the tillering stage (T2, 45%~50% FC), mild drought at the jointing stage (J1, 60%~65% FC), and mild drought at the jointing stage (J2, 45%~50% FC) as the sub-zones.

Results: The dry matter accumulation of the aboveground parts of wheat (stem sheaths, leaves, and spikes), the transfer rate and contribution rate of nutrient organs, the maximum filling rate (V), and the mean filling rate (V) increased significantly after re-watering in the T1 treatment, and decreased with the deepening of the degree of water stress.

View Article and Find Full Text PDF

Iliac Vein Compression Syndrome (IVCS) is a common risk factor for deep vein thrombosis in the lower extremities. The objective of this study was to investigate whether employing a porous medium model to simulate the compressed region of an iliac vein could improve the reliability and accuracy of Computational Fluid Dynamics (CFD) analysis outcomes of IVCS. Pre-operative Computed Tomography (CT) scan images of patients with IVCS were utilized to reconstruct models illustrating both the compression and collateral circulation of the iliac vein.

View Article and Find Full Text PDF

Objectives: To assess the effect of occlusion and implant number/position on stress distribution in Kennedy Class II implant-assisted removable partial denture (IARPD).

Materials And Methods: IARPDs were designed in six models: with one implant (bone level with a platform of 4 mm and length of 10 mm) at the site of (I) canine, (II) between first and second premolars, (III) first molar, (IV) second molar, or two implants at the sites of (V) canine-first molar, and (VI) canine-second molar. A conventional RPD served as control.

View Article and Find Full Text PDF

N, N-dimethyltryptamine (DMT) in rodent brain: Concentrations, distribution, and recent pharmacological data.

Prog Neuropsychopharmacol Biol Psychiatry

January 2025

Louisiana State University, Department of Comparative Biomedical Sciences, Baton Rouge, LA 70803, United States of America. Electronic address:

Renewed interest in the clinical use of psychedelic drugs acknowledges their therapeutic effectiveness. It has also provided a changing frame of reference for older psychedelic drug study data, especially regarding concentrations of N, N-dimethyltryptamine (DMT) reported in rodent brains and recent discoveries in DMT receptor interactions in rat brain neurons and select brain areas. The mode of action of DMT in its newly defined role as a neuroplastogen, its effectiveness in treating neuropsychiatric disorders, and its binding to intracellular sigma-1 and 5HT2a receptors may define these possible roles.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!