At the end of the 19th and the beginning of the 20th century many famous persons stayed on the Croatian coast mostly because of touristic and health reasons, than because of natural beauties, scientific or political reasons. Most often they came from Austro-Hungary, Germany or Russia but also from our homelands. Among them were also many famous doctors, some known worldwide. The most distinguished were the surgeon Theodor Billroth, the bacteriologist and a Nobel prize winner Robert Koch, the pathologist Rudolf Virchow, and the psychiatrist Sigmund Freud. They left a deep impression and a big benefit at the area they stayed in.
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Evaluating academic detailing as an antibiotic stewardship intervention in primary healthcare settings in Croatia.
BMC Prim Care
December 2024
Department of Endocrinology, University hospital Dubrava, Zagreb, Croatia, and School of Medicine, and University of Zagreb, Zagreb, Croatia.
Background: Acute respiratory tract infections are common in primary healthcare care settings and frequently result in antibiotic prescriptions, despite being primarily viral. There is scarcity of research examining impact of academic detailing (AD) intervention on prescribing practices for these infections in resource-constrained healthcare settings like southeastern Europe. Therefore aim of this study was to evaluate impact of AD intervention as an antimicrobial stewardship measure on antibiotic prescribing for acute respiratory tract infections in primary setting in Croatia which is located in southeastern Europe.
View Article and Find Full Text PDFTransplantation of neural stem cells improves recovery of stroke-affected mice and induces cell-specific changes in GSDMD and MLKL expression.
Front Mol Neurosci
August 2024
Laboratory for Stem Cells, Department for Regenerative Neuroscience, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
Introduction: Stroke, the second leading cause of death and disability in Europe, is primarily caused by interrupted blood supply, leading to ischemia-reperfusion (IR) injury and subsequent neuronal death. Current treatment options are limited, highlighting the need for novel therapies. Neural stem cells (NSCs) have shown promise in treating various neurological disorders, including stroke.
View Article and Find Full Text PDFStable methylation loci are associated with systolic blood pressure in a Croatian island population.
Epigenomics
November 2022
Division of Epidemiology, Department of Environmental & Public Health Sciences, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
The objective was to identify stable and dynamic DNA methylation loci associated with cardiometabolic traits among an adult population from the Croatian island of Hvar. An epigenome-wide association study was conducted using peripheral blood longitudinally collected at two time points 10 years apart via Infinium MethylationEPIC beadarray (n = 112). Stable and dynamic loci were identified using linear mixed models.
View Article and Find Full Text PDFAdherence to Mediterranean diet among Lithuanian and Croatian students during COVID-19 pandemic and its health behavior correlates.
Front Public Health
October 2022
Department of Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
Maintaining healthy behavior, especially in times of crisis like the COVID-19 pandemic, is particularly important for staying healthy. Nutrition is an everyday behavior and along with other health-related behaviors is associated with many health outcomes. The aim of this study was to assess and compare adherence to the Mediterranean diet (MedDiet) and particular food choices among the Mediterranean and non-Mediterranean populations of university students and identify its lifestyle correlates at the outburst of the COVID-19 pandemic.
View Article and Find Full Text PDFDistribution of Pathogens and Predictive Values of Biomarkers of Inflammatory Response at ICU Admission on Outcomes of Critically Ill COVID-19 Patients with Bacterial Superinfections-Observations from National COVID-19 Hospital in Croatia.
Diagnostics (Basel)
August 2022
Clinical Department for Anesthesiology, Reanimatology and Intensive Care Medicine, University Hospital Dubrava, 10000 Zagreb, Croatia.
Article Synopsis
- * Methods: Researchers conducted a retrospective analysis over 11 months in a Croatian COVID-19 hospital, examining clinical data and using regression analysis to assess the predictive values of inflammatory biomarkers.
- * Results: More than half (55.3%) of the patients developed superinfections, primarily in the lower respiratory tract. Multidrug-resistant pathogens were prevalent and linked to higher mortality and extended ICU stays, with elevated ferritin and neutrophil counts indicating reduced survival chances.
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