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A 48-year-old Filipino female presented with unilateral acute onset painful red eye, blurred vision and yellow discharge. On examination she had a corrected visual acuity of 6/5 in the right eye and 6/18 in the left eye. There was a left-sided periorbital swelling, with chemosis involving the bulbar conjunctiva on the temporal aspect. Ocular motility showed limitation of left-sided abduction with mild limitation of laevoelevation and laevodepression. She was afebrile and systemic examination was unremarkable. Medical history included diagnosis of Crohn's disease since the age of 20. She was on oral mesalamine 1 g for mildly active colitis. Full blood count was normal but erythrocyte sedimentation rate and C reactive protein were raised. Blood culture and conjunctival swab were negative. Contrast-enhanced CT scan demonstrated enlargement of the lacrimal gland. She was managed conservatively with acetaminophen and codeine for pain and swelling. She recovered completely in 2 weeks with no sequelae.
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http://dx.doi.org/10.1136/bcr.02.2009.1619 | DOI Listing |
Dig Liver Dis
March 2025
Punjab Medical College, Faisalabad Medical University, Pakistan. Electronic address:
Intern Med
March 2025
Department of Pathology, Jichi Medical University Saitama Medical Center, Japan.
Cutaneous arteritis (CA) is a rare cutaneous manifestation of Crohn's disease. A 50-year-old woman with a 15-year history of CA was admitted to our hospital with a fever, abdominal pain, and hematochezia. Based on these symptoms and increased C-reactive protein levels, systemic vasculitis was considered.
View Article and Find Full Text PDFBMJ Open Gastroenterol
March 2025
Department of Gynecology and Obstetrics, University Hospital Centre Toulouse, Toulouse, Occitanie, France.
Objective: Despite guidelines indicating no contraindications for contraceptives in women with inflammatory bowel disease (IBD), this population shows increased voluntary childlessness and lower contraceptive use. Knowledge gaps among healthcare providers on IBD's impact on fertility and contraception may drive these trends. This survey assessed knowledge discrepancies among IBD patients, gastroenterologists (GEs), and women's healthcare providers (WHPs) regarding fertility and contraception.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
March 2025
Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
Background: Inflammatory bowel diseases (IBD); Crohn's disease (CD), ulcerative colitis (UC)) are global diseases. There is a paucity of knowledge about the burden and epidemiology of IBD in Africa. We performed a scoping review of the published literature on IBD in Africa to identify burden, risk factors, and outcomes as well as knowledge gaps.
View Article and Find Full Text PDFGenome wide association studies (GWAS) identify many risks for Crohn's disease (CD), including a site near the metabolism gene laccase domain containing 1 (LACC1). We previously found this site near LACC1 was associated with decreased LACC1 expression in T lymphocytes, yet the mechanism affecting gene expression and its links to T cell function and inflammatory disease were unknown. Here we identify variants in the promoter region that influence transcription of LACC1.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!