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Rising Burden of Colon and Rectum Cancer in China: An Analysis of Trends, Gender Disparities, and Projections to 2030.
Ann Surg Oncol
January 2025
Department of Medical Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian, China.
Background: Colon and rectum cancer (CRC) is a major health burden in China, with notable gender disparities. This study was designed to analyze trends in CRC incidence, prevalence, and mortality from 1990 to 2021 and to project future trends.
Methods: Using data from the Global Burden of Disease (GBD) Study 2021, we examined CRC burden in China, including incidence, prevalence, mortality, disability-adjusted life years (DALYs), years lived with disability (YLDs), and years of life lost (YLLs).
Maternal education and prenatal smoking associations with adolescent executive function are substantially confounded by genetics.
Dev Psychol
January 2025
School of Philosophy, Psychology, and Language Sciences, University of Edinburgh.
Twin studies have suggested extremely high estimates of heritability for adolescent executive function, with no substantial contributions from shared environment. However, developmental psychology research has found significant correlations between executive function outcomes and elements of the environment that would be shared in twins. It is unclear whether these seemingly contradictory findings are best explained by genetic confounding in developmental studies or limitations in twin studies, which can potentially underestimate shared environment.
View Article and Find Full Text PDFSecondhand vape exposure regulation of CFTR and immune function in cystic fibrosis.
Am J Physiol Lung Cell Mol Physiol
January 2025
Division of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Emory University School of Medicine, Atlanta, GA, USA.
Secondhand smoke exposure (SHSe) is a public health threat for people with cystic fibrosis (CF) and other lung diseases. Primary smoking reduces CFTR channel function, the causative defect in CF. We reported that SHSe worsens respiratory and nutritional outcomes in CF by disrupting immune responses and metabolic signaling.
View Article and Find Full Text PDFAssociation between exposure to environmental pollutants and increased oral health risks, a comprehensive review.
Front Public Health
January 2025
Guangdong Provincial Key Laboratory of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China.
The burden of disease and death attributable to environmental pollution is a growing public health challenge worldwide, particularly in developing countries. While the adverse effects of environmental pollution on oral health have garnered increasing attention, a comprehensive and systematic assessment remains lacking. This article delves into the intricate relationship between environmental pollution and oral health, highlighting significant impacts on various aspects such as dental caries, periodontal diseases, oral facial clefts, cancer, as well as other oral diseases.
View Article and Find Full Text PDFMachine Learning-Based Prediction of Binge Drinking among Adults in the United State: Analysis of the 2022 Health Information National Trends Survey.
Proc 2024 9th Int Conf Math Artif Intell (2024)
May 2024
Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06516, USA.
Little is known about the association of social media and belief in alcohol and cancer with binge drinking. This study aimed to perform feature selection and develop machine learning (ML) tools to predict occurrence of binge drinking among adults in the United State. A total of 5,886 adults including 1,252 who ever experienced with binge drinking were selected from the 2022 Health Information National Trends Survey (HINTS 6).
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