The mean wall thickness (MWT), measured by the Kragstrup technique, and the trabecular bone volume (TBV), have been measured in 50 transiliac undecalcified bone biopsies performed in 50 subjects who died suddenly (traffic accident, carbon monoxide, poisoning). Diseases affecting the skeleton were excluded in the autopsies. Our values for MWT were similar to those found in previously published studies except those of Kragstrup's group, in which values are higher. As our measuring technique was that of Kragstrup, these results could be explained either by a difference in staining methods (Solocromo cyanine R and Goldner method respectively) or by the differences in populations considered (French and Danish respectively). Our study confirmed a significant decrease in MWT and TBV with age and a positive correlation between MWT, TBV and age.
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Zhonghua Yi Xue Za Zhi
December 1990
The aim of the present study was to make available the reference data of bone histomorphometric parameters for iliac crest of normal Chinese subjects. 178 subjects were studied, including group A:97 patients with minor orthopaedic disorders (53 males and 44 females) and group B:81 healthy subjects of sudden death (52 males and 29 females). Bone samples were taken from the iliac 2 cm below the crest.
View Article and Find Full Text PDFArch Ital Anat Embriol
February 1991
Clinica Ortopedica, Istituto Scientifico Ospedale S. Raffaele, Milano.
The mean wall thickness (MWT), measured by the Kragstrup technique, and the trabecular bone volume (TBV), have been measured in 50 transiliac undecalcified bone biopsies performed in 50 subjects who died suddenly (traffic accident, carbon monoxide, poisoning). Diseases affecting the skeleton were excluded in the autopsies. Our values for MWT were similar to those found in previously published studies except those of Kragstrup's group, in which values are higher.
View Article and Find Full Text PDFBone Miner
October 1987
Department of Endocrinology, Academisch Ziekenhuis Vrije Universiteit, Amsterdam, The Netherlands.
The prevalence of osteoporosis in patients with hip fracture is not well defined. We performed a histomorphometric analysis of bone structural parameters in transilial biopsies of 39 patients with hip fracture (21 cervical, 18 trochanteric), 23 patients with one or more vertebral crush fractures and 20 control subjects. Trabecular bone volume (TBV) and trabecular surface density (Sv) were significantly lower in trochanteric than in cervical fractures.
View Article and Find Full Text PDFIntermittent administration of antiosteoclastic agents has been proposed in order to increase trabecular bone volume (TBV). We evaluated the effect of two different intermittent schedules of administration of (3 amino-1-hydroxypropylidene)-1, 1 bisphosphonate (AHPrBP) on pig bone remodeling for a period of 60 days. AHPrBP (1.
View Article and Find Full Text PDFWe have compared the mean wall thickness (MWT) and active formation periods (sigma f(A] of trabecular bone packets in iliac crest biopsies from 20 patients (7 male, 13 female) with corticosteroid-induced osteoporosis (CS-OP) and 20 age- and sex-matched controls. The trabecular bone volume (TBV) of the CS-OP patients (9.6% +/- 2.
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