The study investigated the effectiveness of different camouflage designs using a computational image quality index. Camouflaged human targets were presented on a natural landscape and the targets were designed to be similar to the landscape background with different levels of background similarity as estimated by the image index. The targets were presented in front of the observer (central 0 degrees) or at different angles in the left (-7 degrees, -14 degrees, -21 degrees) or right (+7 degrees, +14 degrees, +21 degrees) visual fields. The observer had to detect the target using peripheral vision if the target appeared in the left and right visual fields. The camouflage effectiveness was assessed by detection hit rates, detection times, and subjective ratings on detection confidence and task difficulty. The study showed that the psychophysical measures correlated well with the image similarity index, suggesting a potentially more efficient camouflage effectiveness assessment tool if the relationship between the psychophysical results and the index can be quantified in the future.
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http://dx.doi.org/10.2466/24.PMS.114.2.527-541 | DOI Listing |
Allergy Asthma Proc
January 2025
From the Department of Microbiology-Immunology, Georgetown University Medical Center, Washington, D.C.
Allergen immunotherapy (AIT) is currently the most effective immunologic form of treatment for patients with atopic allergic diseases commonly used by allergist/immunologists to reduce allergic symptoms by gradually desensitizing the immune system to specific allergens. Currently, the primary mechanism of AIT emphasizes the crucial role of immune regulation, which involves a shift from a T-helper type 2 (Th2) cell response, which promotes allergy, to a T-regulatory (Treg) cell population, which inhibits the allergic inflammatory response through the production of immunosuppressive cytokines interleukin 10 and transforming growth factor β, which play pivotal roles in suppressing the allergic reaction. In a series of previous in vitro and in vivo experiments, we have demonstrated the capacity of synthetic methylated cytosine-phosphate-guanine (CpG) oligodeoxynucleotide (ODN) moieties as well as methylated genomic DNA ODN motifs from Bifidobacterium longum subspecies infantis to activate Treg cell differentiation in contrast to the unmethylated ODN moiety, which promotes proinflammatory responses driven by Th17-mediated responses.
View Article and Find Full Text PDFChin Med
December 2024
State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Background: Lovastatin, the main lipid-lowering component in red yeast rice, is a golden anti-lipid drug, but its long-term application is continuously challenged by potential skeletal muscle atrophy. Daidzein, an isoflavone derived from soybeans and many Chinese medicines, shows therapeutic potential in treating muscle-related diseases and metabolic disorders. However, whether daidzein can improve lovastatin-induced muscle atrophy and the specific mechanism needs to further study.
View Article and Find Full Text PDFJ Transl Med
December 2024
Department of Blood Transfusion, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.
Cardiovascular diseases (CVDs) are the leading cause of mortality among individuals with noncommunicable diseases worldwide. Obesity is associated with an increased risk of developing cardiovascular disease (CVD). Mitochondria are integral to the cardiovascular system, and it has been reported that mitochondrial transfer is associated with the pathogenesis of multiple CVDs and obesity.
View Article and Find Full Text PDFBMC Bioinformatics
December 2024
College of Computer and Information Engineering/College of Artificial Intelligence, Nanjing Tech University, Nanjing, 210093, China.
Background: The collection of substantial amounts of electroencephalogram (EEG) data is typically time-consuming and labor-intensive, which adversely impacts the development of decoding models with strong generalizability, particularly when the available data is limited. Utilizing sufficient EEG data from other subjects to aid in modeling the target subject presents a potential solution, commonly referred to as domain adaptation. Most current domain adaptation techniques for EEG decoding primarily focus on learning shared feature representations through domain alignment strategies.
View Article and Find Full Text PDFFood Environ Virol
December 2024
Interdisciplinary Center for River Basin Environment, University of Yamanashi, 4-3-11 Takeda, Kofu, Yamanashi, 400-8511, Japan.
Wastewater surveillance for pathogens is important to monitor disease trends within communities and maintain public health; thus, a quick and reliable protocol is needed to quantify pathogens present in wastewater. In this study, a method using a commercially available magnetic carbon bead-based kit, i.e.
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