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Transient Osteoporosis of Hip (TOH) is an uncommon disorder of idiopathic nature, particularly in the Asian population. It has been described to mostly occur in middle aged men and women in their third trimester of pregnancy. A distinctive hallmark of this condition is that it is self limiting and resolves in a few months. The patient presents to the physician with pain on movement and impaired mobility of the affected joint, developing without any history of trauma. MRI is the main diagnostic tool. We report herein a case of a forty five year old male, who developed transient osteoporosis of the hip, and was managed conservatively.
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J Cutan Med Surg
March 2025
Division of Dermatology, University of Alberta, Edmonton, AB, Canada.
Calcinosis cutis, characterized by the pathological deposition of insoluble calcium salts in the skin, is associated with several disease entities, particularly autoimmune conditions such as scleroderma and dermatomyositis. Lesions of calcinosis are often painful, prone to ulceration, and significantly impair quality of life. Despite the clinical impact, no effective treatments have been established to date, making prevention of this condition a critical priority.
View Article and Find Full Text PDFCureus
February 2025
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, JPN.
We report the case of a 44-year-old male patient without a notable medical history who developed transient osteoporosis following surgery for a medial malleolus fracture, which led to a stress fracture and osteonecrosis, ultimately requiring total talar replacement. The patient sustained the fracture spraining his ankle while welding. Osteosynthesis was performed using two cannulated cancellous screws, whereas bone union was achieved 3.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
March 2025
Bronchial asthma (asthma) is a common chronic respiratory disease. Standardized diagnosis, treatment and effective clinical management are critical to improving asthma control, improving patients' quality of life, and reducing the disease burden. Based on the latest evidence-based research from both domestic and international references, the Asthma Group of the Chinese Thoracic Society has revised the " ()".
View Article and Find Full Text PDFOrthopadie (Heidelb)
February 2025
Orthopädische Klinik des Centre Hospitalier de Luxembourg, Akademisches Lehrkrankenhaus der Universitätskliniken des Saarlandes, 78, rue d' Eich, 1460, Luxembourg, Luxemburg.
Background: The frequent use of magnetic resonance imaging (MRI) introduced "bone marrow edema" (BME) as a descriptive radiological term for hyperintense signal changes in fluid-sensitive sequences. With the optimization of MRI soft tissue contrast, BME has evolved into a valid prognostic indicator associated with pain genesis, trauma, mechanical overload, and progressive cartilage and joint destruction.
Diagnostics: Both osteonecrosis and BME manifest in early MRI as intraosseous fluid accumulation, characterized by hyperintense signals in T2-weighted and STIR sequences.
Int Urol Nephrol
January 2025
Nephrology, Dialysis and Kidney Transplant Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Introduction: Kidney transplantation is the preferred treatment for end-stage kidney disease (ESKD), enhancing survival and quality of life. However, kidney transplant recipients (KTRs) are at high risk for bone disorders, particularly low bone turnover disease, which increases fracture risk. Teriparatide, an anabolic agent, may provide a beneficial treatment option for these patients.
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