AI Article Synopsis
- A 7-year-old longhaired dachshund treated with cyclosporine for immune-mediated hemolytic anemia developed gingival mass lesions after 600 days of treatment.
- Histopathological analysis revealed that these lesions were due to hyperplastic suppurative gingivitis.
- Following a reduction in cyclosporine dosage, the dog's anemia improved and the gingival lesions significantly decreased in size and ultimately disappeared, indicating they were likely an adverse effect of the medication.
Article Abstract
Gingival mass lesions developed when cyclosporine was administered for 600 days to a female, 7-year-old, longhaired dachshund diagnosed with intractable immune-mediated hemolytic anemia (IMHA). Histopathology indicated hyperplastic suppurative gingivitis. As the anemia improved, the dosage of cyclosporine A (CsA) was markedly decreased, and the mass lesions decreased in size and disappeared, thus suggesting that the mass lesions were an adverse reaction to CsA.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239152 | PMC |
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