The study involved 178 children aged 7-14 with mild or moderate-severity spastic diplegia and hemiparetic infantile cerebral paralysis (ICP) exposed to UHF electric field. The effect of this modality incorporation into ICP combined treatment was evaluated with regard to clinical manifestations, hemo- and cerebrospinal fluid dynamics, bioelectric activity of the brain, psychic functions, immunological reactivity, sympathetic-adrenal activity. There was a positive trend in the clinical and paraclinical parameters studied.
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Children (Basel)
December 2024
Department of Sensory Organs, Institute of Biochemistry and Cell Biology (IBBC-CNR), Sapienza University of Rome, 00185 Rome, Italy.
Neurodevelopmental disorders represent an important and complex area of pediatric medicine, including a wide range of conditions affecting brain and nervous system functioning during development [...
View Article and Find Full Text PDFChildren (Basel)
December 2024
Nursing and Podiatry, Facultad de Ciencias de la Salud, University of Málaga, 29071 Málaga, Spain.
Background: Flexible pediatric flatfoot is an anatomical presentation of the foot that is common in children, and its functional impact raises long-term uncertainty. Functional re-education includes strengthening and stretching exercises for the intrinsic and extrinsic musculature of the foot, proposed as an effective conservative treatment. However, to date, there is no systematic review examining its effectiveness in the pediatric population.
View Article and Find Full Text PDFChilds Nerv Syst
January 2025
Division of Neurosurgery, Department of Surgery, National University Hospital of Singapore, 5 Lower Kent Ridge Rd, Singapore, 119074, Singapore.
Congenital infantile brainstem high-grade gliomas (HGGs) are extremely rare. Given the limited literature characterizing this disease, management of these tumors remains challenging. Brainstem HGGs are generally associated with extremely poor prognosis.
View Article and Find Full Text PDFFront Pediatr
January 2025
Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Introduction: Infantile Epileptic Spasms Syndrome (IESS) typically has a profound impact on the neurodevelopment of patients. The study on IESS indicates possible geographical variation in etiology and a lack of data from China. Our study intends to summarize the etiology of IESS and analyze its characteristics.
View Article and Find Full Text PDFJ Clin Invest
January 2025
Department of Pharmacology, University of Michigan Medical School, Ann Arbor, United States of America.
Dravet syndrome (DS) is a developmental and epileptic encephalopathy (DEE) that begins in the first year of life. While most cases of DS are caused by variants in SCN1A, variants in SCN1B, encoding voltage-gated sodium channel β1 subunits, are also linked to DS or to the more severe early infantile DEE. Both disorders fall under the OMIM term DEE52.
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