[Acute respiratory distress syndrome related to intra-alveolar hemorrhage revealing a vasculitis].

Rev Pneumol Clin

Service de Pneumologie, Hôpital Pontchaillou, Centre Hospitalier Universitaire de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France.

Published: October 2012

Intra-alveolar hemorrhage (IAH) could be revealed by acute respiratory failure. The classic association of hemoptysis - anemia - radiological infiltrates is suggestive and has to be confirmed by broncho-alveolar lavage with Golde score. Etiologies included immune and non-immune diseases, with specific treatment for each. We report a case of IAH revealed by acute respiratory distress syndrome and anemia (3 g/dL), related to pulmonary and cerebral vasculitis without renal involvement. The patient was efficiently treated with corticosteroids and cyclophosphamide. This case highlights the critical role of BAL cytological analysis with Golde score, and the need for a rapid and accurate diagnosis in order to guide specific treatment. If histology is needed, renal biopsy even without renal involvement, or surgical lung biopsy is possible.

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http://dx.doi.org/10.1016/j.pneumo.2012.04.002DOI Listing

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