Activation of NF-κB transcription factor is crucial for survival, proliferation, and differentiation of T cells. In this issue of Immunity, Paul et al. (2012) demonstrate that autophagy is a pathway by which TCR-activated NF-κB is turned over.
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http://dx.doi.org/10.1016/j.immuni.2012.06.008 | DOI Listing |
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