Dampening NF-κB signaling by "self-eating".

Immunity

Department of Molecular and Cellular Oncology, University of Texas, M.D. Anderson Cancer Center, Houston, TX 77030, USA.

Published: June 2012

Activation of NF-κB transcription factor is crucial for survival, proliferation, and differentiation of T cells. In this issue of Immunity, Paul et al. (2012) demonstrate that autophagy is a pathway by which TCR-activated NF-κB is turned over.

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Source
http://dx.doi.org/10.1016/j.immuni.2012.06.008DOI Listing

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