The central hemodynamics was studied and compared in 20 patients with hypertrophic cardiomyopathy (HCMP) at rest, during bicycle ergometry (BEM) and transesophageal pacing of the atria (TEPA). According to the BEM readings, HCMP patients did not show any material differences from normals' reaction to exercise on the part of the volumetric and hemodynamic parameters as well as left ventricle contractile function. At the same time as revealed by TEPA, HCMP patients did manifest differences from normals' response in the hemodynamics and myocardial contractility. Alterations that occur in HCMP patients undergoing TEPA in response to an isolated increase of frequency of the cardiac rhythm are likely to reflect latent disorders of systolic function of the asymmetric hypertrophied left ventricle which is not capable of making adequate volumetric and functional restructure.
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