Abnormal spiral arteries modification in stillbirths: the role of maternal prepregnancy body mass index.

J Matern Fetal Neonatal Med

Department of Obstetrics and Gynecology, DMSD San Paolo, University of Milano, Via A. di Rudini 8, 20142Milano, Italy.

Published: December 2012

AI Article Synopsis

  • The study evaluated the prevalence of abnormal spiral arteries modification (ASAM) in 203 stillbirth cases and its connections to maternal health.
  • ASAM was found in 33.9% of the cases, with a significant link to higher prepregnancy BMI among affected mothers.
  • The findings highlight the importance of encouraging weight loss in obese women prior to pregnancy to reduce negative outcomes.

Article Abstract

Aim: To evaluate the prevalence of abnormal spiral arteries modification (ASAM) in stillbirths and its anatomo-clinical correlations.

Methods: Two-hundred and three placentas of stillbirth ≥20 weeks of gestation were analyzed.

Results: ASAM was present in 69/203 cases (33.9%). The only maternal characteristic that significantly differed in ASAM versus normal spiral arteries modification (NSAM) cases was the prepregnancy body mass index (BMI) (25.9 ± 6.1 and 23.1 ± 4.2 kg/m(2), respectively) with 15.9% of obesity in ASAM mothers versus 5.2% in NSAM (p = 0.02).

Conclusion: Given the association between obesity and adverse pregnancy outcome, our data suggest that counselling obese women to lose weight before pregnancy becomes increasingly imperative.

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Source
http://dx.doi.org/10.3109/14767058.2012.705395DOI Listing

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