Falling apart, on cue: Signaling pathways often display a profound spatiotemporal component that is best studied using light-activatable reagents. Three separate photolabile moieties that can be distinguished based upon their response to three distinct wavelengths (360, 440, and 560 nm) have been synthesized and evaluated. This tri-color system is also applied to imaging in microwells and HeLa cells (see picture).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523745 | PMC |
| http://dx.doi.org/10.1002/anie.201202820 | DOI Listing |
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