We define a signal-to-noise ratio (SNR) for eye aberrometry in terms of the sensor geometry, measurement noise, and population statistics. The overall estimation error is composed of three main contributions: the bias in the estimated modes, the truncation error, and the error due to the noise propagation. This last term can be easily parametrized by the proposed SNR. We compute the overall error as well as the magnitude of its three components for a typical sensor configuration, population statistics, and different SNR. We show that there are an optimum number of Zernike aberration modes to be retrieved in each case.
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http://dx.doi.org/10.1364/OL.37.002427 | DOI Listing |
Angew Chem Int Ed Engl
January 2025
East China University of Science and Technology, Insitute of Fine Chemicals, Meilong Road 130, Shanghai, China, 200237, Shanghai, CHINA.
Protein clustering/disassembling is a fundamental process in biomolecular condensates, playing crucial roles in cell fate decision and cellular homeostasis. However, the inherent features of protein clustering, especially for its reversible behavior and subtle microenvironment variation, present significant hurdles in probe chemistry for tracking protein clustering dynamics. Herein, we report a bilateral-tailored chemigenetic probe, in which an "amphiphilic" AIEgen QMSO3Cl is covalently conjugated to a protein tag that is genetically fused to protein-of-interest (POI).
View Article and Find Full Text PDFFront Oncol
January 2025
Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Purpose: Recent deep-learning based synthetic computed tomography (sCT) generation using magnetic resonance (MR) images have shown promising results. However, generating sCT for the abdominal region poses challenges due to the patient motion, including respiration and peristalsis. To address these challenges, this study investigated an unsupervised learning approach using a transformer-based cycle-GAN with structure-preserving loss for abdominal cancer patients.
View Article and Find Full Text PDFCases abound in which nearly identical traits have appeared in distant species facing similar environments. These unmistakable examples of adaptive evolution offer opportunities to gain insight into their genetic origins and mechanisms through comparative analyses. Here, we present a novel comparative genomics approach to build genetic models that underlie the independent origins of convergent traits using evolutionary sparse learning.
View Article and Find Full Text PDFInt J Ophthalmol
January 2025
Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Aim: To evaluate the effect of femtosecond laser small incision lenticule extraction (SMILE) on the binocular visual function in myopic patients with glasses-free three-dimensional (3D) technique.
Methods: Totally 50 myopic patients (39 females and 11 males) with SMILE were enrolled in this prospective study. The glasses-free 3D technique was used to evaluate the binocular visual function in these subjects including static stereopsis, dynamic stereopsis, foveal suppression, and binocular balance point of signal to noise ratio (s/n ratio).
Nanoscale
January 2025
School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.
Low-frequency noise in detection systems significantly affects the performance of ultrasensitive and ultracompact spin-exchange relaxation-free atomic magnetometers. High frequency modulation detection helps effectively suppress the 1/ noise and enhance the signal-to-noise ratio, but conventional modulators are bulky and restrict the development of integrated atomic magnetometer modulation-detection systems. Resonant metasurface-based thin-film lithium-niobate (TFLN) active optics can modulate free-space light within a compact configuration.
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