AI Article Synopsis
- The "RNA world" hypothesis, which suggests that life began with ribozymes, is currently the leading theory about the origin of life and genetic information.
- However, this hypothesis has limitations that need to be addressed.
- To explore alternatives, researchers are considering theories related to the hydrothermal origin of life, the solubility of RNA and similar biopolymers, and creating evolutionary systems similar to in vitro selection methods for functional RNA based on molecular biology.
Article Abstract
Following the discovery of ribozymes, the "RNA world" hypothesis has become the most accepted hypothesis concerning the origin of life and genetic information. However, this hypothesis has several drawbacks. Verification of the hypothesis from different viewpoints led us to proposals from the viewpoint of the hydrothermal origin of life, solubility of RNA and related biopolymers, and the possibility of creating an evolutionary system comparable to the in vitro selection technique for functional RNA molecules based on molecular biology.
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| http://dx.doi.org/10.1016/j.biochi.2012.02.017 | DOI Listing |
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