Experience in 155 replantations of large segments of the extremities is discussed. The results of treatment are analysed from the standpoint of anoxia of the separated segments of the extremities. A case of replantation of the lower extremity (shin) with 42-hour anoxia is described. It is concluded that increased risk of replantation of large segments of extremities is determined in the first place by traumatic and hemorrhagic shock and not by the so-called transplantation toxicosis.

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