The use of immunotherapy to treat cancer is rapidly gaining momentum. Using pre-clinical mouse models, we have recently demonstrated potent and long lasting tumor regression can be elicited by immune-stimulating monoclonal antibodies (mAbs) when combined with histone deacetylase inhibitors (HDACi) and believe this therapy will have broad application in humans.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382866 | PMC |
http://dx.doi.org/10.4161/onci.18804 | DOI Listing |
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