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Real-World Outcomes of a Loading Phase with Intravitreal Faricimab in Neovascular Age-Related Macular Degeneration (n-AMD) and Diabetic Macular Edema (DME).
Ophthalmol Ther
August 2024
Department of Ophthalmology, Policlinico Riuniti Foggia, University of Foggia, 71122, Foggia, Italy.
Introduction: The aims of this work were to evaluate the real-world efficacy and safety of a loading dose of intravitreal faricimab in eyes with active neovascular age-related macular degeneration (n-AMD) or diabetic macular edema (DME) and to analyze the treatment outcome in relation to specific biomarkers.
Methods: Patients with active n-AMD or DME, treated with four monthly intravitreal injections of faricimab, were enrolled in this retrospective, uncontrolled study. Best-corrected visual acuity (BCVA), central subfield thickness (CST), presence of retinal fluid (RF) on optical coherence tomography (OCT), and adverse events were assessed at baseline and at weeks 4, 8, 12, and 16.
Self-Supervised Learning for Improved Optical Coherence Tomography Detection of Macular Telangiectasia Type 2.
JAMA Ophthalmol
March 2024
Department of Ophthalmology, University of Washington, Seattle.
Importance: Deep learning image analysis often depends on large, labeled datasets, which are difficult to obtain for rare diseases.
Objective: To develop a self-supervised approach for automated classification of macular telangiectasia type 2 (MacTel) on optical coherence tomography (OCT) with limited labeled data.
Design, Setting, And Participants: This was a retrospective comparative study.
Recurrence risk of myopic choroidal neovascularisation: a systematic review of current study.
BMJ Open Ophthalmol
October 2023
Research Assistant, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Introduction: The rising prevalence of myopia is a concern in ophthalmology, with myopic choroidal neovascularisation (m-CNV) significantly affecting vision. However, long-term outcomes of m-CNV management have been unsatisfactory, leading to high recurrence rates. These studies aim to identify risk factors for m-CNV recurrence.
View Article and Find Full Text PDFAn unusual presentation of macular telangiectasia type 2 with a large pigment deposit.
GMS Ophthalmol Cases
January 2021
Department of Vitreo Retina, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.
Macular telangiectasia type 2 (MacTel) is a bilateral retinal disease that seems to be limited to the juxtafoveal region of the macula. We herein report an unusual presentation of MacTel with a large pigment deposit at the macula. Fundus of the right eye showed a large pigment deposit at the macula and right-angled venule.
View Article and Find Full Text PDFOPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF CONGENITAL SIMPLE HAMARTOMA OF THE RETINAL PIGMENT EPITHELIUM.
Retin Cases Brief Rep
March 2020
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania.
Purpose: To describe the optical coherence tomography angiography features of congenital simple hamartoma of the retinal pigment epithelium.
Methods: Case report.
Results: A 14-year-old boy was referred for an asymptomatic fundus tumor in the left eye.
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