Lakartidningen
Neurologiska kliniken, Karolinska universitetssjukhuset, Huddinge.
Published: July 2012
Muscle Nerve
March 2025
Department of Neurology, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.
Introduction/aims: Prolonged distal median motor latency (DML) may occur in carpal tunnel syndrome (CTS), potentially causing an electrodiagnostic dilemma in acquired demyelinating polyneuropathies. We aimed to demonstrate that parameter values obtained from conventional median nerve conduction studies can distinguish immune-mediated demyelination from compression-induced damage.
Methods: We retrospectively reviewed the median nerve records of 73 control individuals, 125 patients with pure CTS, 31 with CTS and diabetic distal symmetric polyneuropathy, 36 with acute inflammatory demyelinating polyneuropathy, and 23 with chronic inflammatory demyelinating polyneuropathy.
Brain Nerve
March 2025
Department of Neurology, JR Tokyo General Hospital.
Chronic inflammatory demyelinating polyradiculoneuropathy includes various pathologies; therefore, the symptoms and course of patients are not uniform. Maintenance therapies such as intravenous and subcutaneous immunoglobulin have been introduced and require continuous outpatient care. A detailed explanation of the disease and shared decision-making with the patient are necessary to provide the best treatment for each patient.
View Article and Find Full Text PDFJ Neurol Sci
February 2025
Department of Neurology, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Introduction: Beta-trace protein (BTP) is primarily used as a marker for traumatic CSF leakage. Spinal leptomeningeal cells adjacent to the spinal nerve roots are a major producer of this protein, which has prompted interest in its relevance to inflammatory polyradiculoneuropathies. BTP has not previously been investigated in patients with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculopathy (CIDP).
View Article and Find Full Text PDFFront Neurol
February 2025
South Western Sydney Local Health District, Sydney, NSW, Australia.
Background And Aims: During the COVID-19 pandemic, vulnerable populations faced worsening mental and physical well-being due to limited access to support systems and diverted health resources during lockdowns. Individuals with chronic neurological disorders including motor neuron disease (MND), chronic inflammatory demyelinating polyneuropathy (CIDP), and multifocal motor neuropathy (MMN) were at considerable risk of severe COVID-19 symptoms. The present study aimed to examine the psychological and physical impact of lockdowns on individuals with MND and other chronic neuromuscular disorders (non-MND).
View Article and Find Full Text PDFPharmacoepidemiol Drug Saf
March 2025
Harvard Medical School, Boston, Massachusetts, USA.
Purpose: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare autoimmune condition of the peripheral nervous system. The validity of the CIDP diagnosis code in claims data is unclear.
Methods: We conducted a validation study testing the performance of claims-based algorithms in identifying CIDP cases, using electronic health record data from the Mass General Brigham Integrated Health Care System linked with Medicare claims data from 01/01/2008 to 12/31/2020.
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