Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionikuv3fhe6m9i3bpr6o0n5tuaq0s7gckb): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3145
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Intra-articular injections are part of long-standing symptomatic treatment of osteoarthritis. Numerous products were injected into arthritic joints to whether analgesic, anti-inflammatory or disease-modifying antirheumatic drug. Corticosteroids and viscosupplements are the only permitted as they are validated by controlled studies and part of the treatment of osteoarthritis recommended by scientific societies. The intra-articular injections are effective in limb osteoarthritis, short term for corticosteroids, in the longer term but more delayed, smaller and less constant for viscosupplements, provided they are properly performed. These local treatments do not have to summarize the treatment of osteoarthritis, but integrated into a comprehensive care without neglecting the non-pharmacologic measures. Their benefit should be reassessed regularly for each patient and their effectiveness is often decreased with the progression of osteoarthritis when it does not stabilize. The injection conditions must be rigorous to ensure greater efficiency and reduce the side effects which are rare and usually benign.
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