AI Article Synopsis
- * An alumina ceramic vessel was designed for this method, allowing for the remote dissolution of irradiated yttrium powder and purification of Zr-89 using automated processes.
- * Results showed that the ceramic vessel produced Zr-89 with high purity and yield, demonstrating its effectiveness and potential for future radionuclide production.
Article Abstract
Introduction: As the use of metallic radionuclides increases, so does the demand for a simple production method. In this study, we demonstrated an in situ target processing concept for automated metallic radionuclide production without the use of any robotic device.
Methods: An alumina ceramic vessel for a vertical irradiation system was designed and developed. The ceramic vessel was evaluated by the production of Zr-89 using an yttrium powder target. The irradiated Y was dissolved remotely in HCl in the ceramic vessel and transferred as a solution to a hotcell through a Teflon tube. The crude Zr-89 was then purified by an automated apparatus. The Zr-89 was eluted with 100 μL of oxalic acid (solution) as the final product.
Results: The ceramic vessel gave a sufficient yield of Zr-89 (57±11MBq/μAh), showed good operability, and could be reused up to 10 times. With nominal irradiation (10μA×2h) in ~90 μL, the product (~940MBq) was obtained with >99.9% radionuclidic purity.
Conclusion: The combination of the ceramic vessel and vertical irradiation has great potential for the remote production of various metallic radionuclides.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.nucmedbio.2012.05.010 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!