Th2-type inflammation has been proposed to facilitate tumor growth. In De Monte et al. (J Exp Med 208:469-478, 2011) we identify in pancreatic cancer a complex cytokine/chemokine cross-talk within the tumor microenvironment mediating Th2 immune-deviation and show that the ratio of Th2/Th1 tumor infiltrating lymphocytes is an independent predictive marker of patients survival.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376960 | PMC |
http://dx.doi.org/10.4161/onci.1.1.17939 | DOI Listing |
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