Aim: To investigate the reliability of massive hepatectomy models by using clip techniques.
Methods: We analyzed anatomical findings in 100 mice following massive hepatectomy induced by liver reduction > 70%. The impact of various factors in the different models was also analyzed, including learning curves, operative time, survival curves, and histopathological findings.
Results: According to anatomical results, models with 75%, 80%, and 90% hepatectomy produced massive hepatectomy. Learning curves and operative times were most optimal with the clip technique. Each hepatectomy performed using the clip technique produced a reasonable survival curve, and there were no differences in histopathological findings between the suture and clip techniques.
Conclusion: Massive hepatectomy by the clip technique is simple and can provide reliable and relevant data.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374979 | PMC |
| http://dx.doi.org/10.3748/wjg.v18.i22.2767 | DOI Listing |
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