Pseudoepitheliomatous hyperplasia is a benign condition defined by an exuberant proliferation of the epithelium with downward progression into the dermis. It may occur in reaction to several conditions including chronic cutaneous wound. We describe an unusual case of a florid pseudoepitheliomatous hyperplasia mimicking a well-differentiated squamous cell carcinoma, restricted to the red part of a rose tattoo.
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http://dx.doi.org/10.1111/j.1742-481X.2012.01013.x | DOI Listing |
J Surg Case Rep
January 2025
Department of Dermatology, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo, Zhejiang 315010, China.
Pseudoepitheliomatous hyperplasia (PEH) is a rare histopathological reaction. Cases of PEH have been infrequently reported, and it's even rare to appear as a postsurgical complication. This case report describes the development of multiple masses and purulent discharge around an abdominal scar following surgery for hepatocellular carcinoma, which morphologically resembles squamous cell carcinoma (SCC), though pathology revealed no signs of malignancy.
View Article and Find Full Text PDFAm J Dermatopathol
December 2024
Department of Dermatology, Warren Alpert Medical School of Brown University, Providence, RI.
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic dermatosis that is difficult to diagnose due to non-specific clinical, laboratory, and histopathologic features. Distinguishing pseudoepitheliomatous hyperplasia (PEH) from squamous cell carcinoma (SCC) is also histopathologically challenging. The connection between PEH and PG is not well recognized, and instances of PG mimicking SCC are rare.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
January 2025
The Operation Eyesight Universal Institute for Eye Cancer, Ophthalmic Pathology Laboratory, LV Prasad Eye Institute, Hyderabad, India.
A 40-year-old woman presented with a mass in her OS for 2 years. Examination revealed a large conjunctival lesion on the nasal bulbar conjunctiva OS and a small upper tarsal conjunctival lesion in the OD. Biopsy OD revealed inflammatory granulation tissue, and OS revealed pseudoepitheliomatous hyperplasia with granulation tissue.
View Article and Find Full Text PDFIndian J Dermatol
October 2024
Department of Dermatology, Institute of Child Health, Kolkata, India.
Introduction: Deep mycoses acquired by penetrating trauma to the skin can have varied and sometimes atypical morphological presentations resulting in diagnostic dilemmas and delay in treatment onset. Histopathology can be a useful tool in not only diagnosing but also differentiating various deep mycoses.
Aims And Objectives: To observe various morphological presentations and histopathological features of deep fungal infections.
Cureus
October 2024
Family Medicine, St. Joseph's Regional Medical Center, Paterson, USA.
This is the case of chronic chromoblastomycosis (CBM) in a 61-year-old male from the Dominican Republic (DR) with extensive cutaneous eruptions over multiple areas of the body including bilateral lower extremities and the flank extending to the back. A 61-year-old male with a history of morbid obesity, chronic kidney disease stage III, and well-controlled hypertension presented to the family medicine clinic for the evaluation of chronic painful skin lesions on his legs and torso. The lesions began 19 years prior, following a flood in the Dominican Republic (DR) where he was living at the time.
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