AI Article Synopsis
- The study examines the effectiveness of FDG-PET scans in detecting recurrent liver metastases after radiofrequency ablation (RFA).
- It analyzes data from nine articles, revealing a sensitivity of 0.73 and specificity of 0.85, indicating reasonably reliable detection rates.
- The findings support using PET/CT scans as a valuable method for monitoring patients after RFA, particularly for those with surgical RFA and colorectal metastases.
Article Abstract
Context: Scanty reports have focused on FDG-PET after radiofrequency ablation (RFA), for recurrence of hepatic metastases.
Objective: To assess FDG-PET diagnostic accuracy on detection of recurrent hepatic lesions.
Methods: After a comprehensive search of PubMed and EMBASE, we performed a patient-based diagnostic meta-analysis of post-RFA FDG-PET.
Results: Across nine included articles, independent, random-effects sensitivity and specificity were 0.73(0.50-0.88) and 0.85(0.72-0.93), respectively. A symmetrical SROC curve was produced with no significant heterogeneity. Specificity was optimal for surgical RFA and colorectal origin of metastases.
Conclusion: Synthesis of published evidence suggests PET/CT as an appropriate tool for optimizing post-ablation follow-up.
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| http://dx.doi.org/10.3109/1354750X.2012.699553 | DOI Listing |
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