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In the early terms of pregnancy anti-infectious protection provides by NK-cells of deciduas. The distribution of immunocompetent cells in the deciduas of women at 6-8 week of gestation and different infections has been studied by immunohisyochemical method. The quantity of NK-cells with CD56 +/- CD16+ CD3- phenotype significant decreased at mycoplasmas infection. Clamidiosis correlated with 2-folder increasing of CD56+/- CD16+ CD3- cells. The quantity of CD56++ CD16- CD3- cells in the deciduas didn't differ between compared groups. The revealed changes in local immunity are accompanied by infringement of gestational transformation, especially under clamidiosis.
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