A Highly Selective Vanadium Catalyst for Benzylic C-H Oxidation.

Chem Sci

Division of Chemistry, Department of Biochemistry, The University of Texas Southwestern Medical Center, Dallas, Texas, 75390, USA; ; Tel: +1 214 6485048.

Published: January 2012

Vanadium complexes have been used extensively to catalyze olefin and alcohol oxidation. However, their application in C-H oxidation has not been well-studied. We report herein that commercially available Cp(2)VCl(2) catalyzes benzylic C-H oxidation selectively and effectively, giving no aromatic oxidation products.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375726PMC
http://dx.doi.org/10.1039/C2SC20178JDOI Listing

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