Thyroxine (T4) inhibits the development of lipid metabolism disorders and experimental atherosclerosis in rabbits (model N.N. Anichkov). The study of the hypothalamic-pituitary system, thyroid, and the microvascular bed also revealed a beneficial effect of thyroxine on their morpho-functional state. Thus, the role of neuroendocrine regulation and disorders of microcirculation in atherogenesis shown.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Stevioside mitigates metabolic dysregulation in offspring induced by maternal high-fat diet: the role of gut microbiota-driven thermogenesis.
Gut Microbes
December 2025
College of Food Science and Engineering, Northwest A&F University, Yangling, China.
Maternal obesity poses a significant threat to the metabolic profiles of offspring. Microorganisms acquired from the mother early in life critically affect the host's metabolic functions. Natural non-nutritive sweeteners, particularly stevioside (STV), play a crucial role in reducing obesity and affecting gut microbiota composition.
View Article and Find Full Text PDFMembrane Surface Charge, Phospholipids, and Protein Localization.
Rev Physiol Biochem Pharmacol
January 2025
Institute of Medical Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Cell membranes contain multiple charged lipids that bind proteins dynamically and their spatial organization on the inner/outer membrane leaflet, or in spatially localized areas has considerable biological importance. Myristoylated alanine-rich C kinase substrate (MARCKS) proteins and their roles as electrostatic switches are one example covered. Cell surface charge needs to be monitored and regulated continually and the roles of lipid flippases and scramblases and their electrical regulation also are considered.
View Article and Find Full Text PDFImmune response accelerated telomere shortening during early life stage of a passerine bird, the blue tit ().
Biol Lett
January 2025
Cluster of Biomolecular Science, Division of Toxicology, Wageningen University and Research, 6708 WE Wageningen, The Netherlands.
Dealing with infections is a daily challenge for wild animals. Empirical data show an increase in reactive oxygen species (ROS) production during immune response. This could have consequences on telomere length, the end parts of linear chromosomes, commonly used as proxy for good health and ageing.
View Article and Find Full Text PDFMitochondrial quality control: Biochemical mechanism of cardiovascular disease.
Biochim Biophys Acta Mol Cell Res
January 2025
Department of Veterinary Sciences, University of Messina, 98168 Messina, Italy. Electronic address:
Mitochondria play a key role in the regulation of energy homeostasis and ATP production in cardiac cells. Mitochondrial dysfunction can trigger several pathological events that contribute to the development and progression of cardiovascular diseases. These mechanisms include the induction of oxidative stress, dysregulation of intracellular calcium cycling, activation of the apoptotic pathway, and alteration of lipid metabolism.
View Article and Find Full Text PDFPhylogenetic and lipid metabolic differences between migratory and Egyptian-domesticated Mallard ducks (Anas platyrhynchos).
Comp Biochem Physiol A Mol Integr Physiol
January 2025
Faculty of Science, Damietta University, New Damietta 34517, Egypt. Electronic address:
Although a giant Egyptian domestic non-migratory duck breed is phenotypically identical to the migratory Mallard, yet it is three times larger. The current study sought to determine the genetic and metabolic differences between this duck and Mallard, which arrives in Egypt in September for wintering and departs in March. Mitochondrial DNA control region (D-loop) was extracted, amplified, sequenced, and analyzed in both ducks.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!