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Extracellularly Released Calreticulin Induced by Endoplasmic Reticulum Stress Impairs Syncytialization of Cytotrophoblast Model BeWo Cells.
Cells
May 2021
Department of Biochemistry, Wakayama Medical University School of Medicine, 811-1 Kimiidera, Wakayama 641-8509, Japan.
The pregnancy-specific syndrome preeclampsia is a major cause of maternal mortality throughout the world. The initial insult resulting in the development of preeclampsia is inadequate trophoblast invasion, which may lead to reduced maternal perfusion of the placenta and placental dysfunction, such as insufficient trophoblast syncytialization. Endoplasmic reticulum (ER) stress has been implicated in the pathology of preeclampsia and serves as the major risk factor.
View Article and Find Full Text PDFEffect of asbestos exposure on differentiation and function of cytotoxic T lymphocytes.
Environ Health Prev Med
October 2020
Department of Hygiene, Kawasaki Medical School, Kurashiki, 701-0192, Japan.
Asbestos exposure is known to cause malignant mesothelioma, which is associated with poor prognosis. We focused on and examined the effect of asbestos exposure on the differentiation and function of cytotoxic T lymphocytes (CTLs). CTLs have the ability to specifically attack tumor cells after being differentiated from naïve CD8 T cells following antigen stimulation.
View Article and Find Full Text PDF[Induction of TOKUTEI NURSE (tentative name) on perspective of experienced nurse in Japan and the United States].
Nihon Geka Gakkai Zasshi
May 2012
Department of Nursing, Osaka Kosei-Nenkin Hospital. Osaka, Japan.
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