A 63-year old patient who had suffered from mild lymphomatoid papulosis with periods of relapse and spontaneous remissions is presented. After 23 years of that chronic dermatosis he developed a malignant lymphoma covering skin, lymph nodes and internal organs, which was confirmed by histopathological examination. Despite intensive chemo and X-ray therapy the patient died. The importance of continuous follow-up of usually benign lymphomatoid papulosis is stressed.
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- Primitive cutaneous T-cell lymphomas are skin-specific lymphomas, distinct from systemic lymphomas affecting the skin.
- The most common types include mycosis fungoides, CD30+ lymphoproliferations, and erythrodermic T-cell lymphomas, with several rarer forms also identified.
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