A mode of formation of wide fields of fast electrons at LUE-25 accelerator is proposed to expose uniformly the extended 4 cm thick biological objects. Dosimetric characteristics of the electron beams have been studied by film and ferrous-sulfate dosimeters. The potencies and limitations of using the dosimeters as a "witness" are discussed.
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Cancers (Basel)
December 2024
Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, Australia.
: Brain cancer is notoriously resistant to traditional treatments, including radiotherapy. Microbeam radiation therapy (MRT), arrays of ultra-fast synchrotron X-ray beams tens of micrometres wide (called peaks) and spaced hundreds of micrometres apart (valleys), is an effective alternative to conventional treatments. MRT's advantage is that normal tissues can be spared from harm whilst maintaining tumour control.
View Article and Find Full Text PDFFront Oncol
December 2024
Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, and Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Front Oncol
December 2024
Institute of Radiation Medicine (IRM), Helmholtz Zentrum München GmbH, German Research Center for Environmental Health, Neuherberg, Germany.
Pract Radiat Oncol
December 2024
Mayo Clinic, Department of Radiation Oncology, Rochester, MN 55905.
Objectives: Spatially fractionated radiation therapy (SFRT) intentionally delivers a heterogeneous dose distribution characterized by alternating regions of high and low doses throughout a tumor. This modality may enhance response to subsequent whole tumor radiation in bulky and radioresistant lesions that are historically less responsive to conventional radiation doses alone. The current study presents a single institution experience with modern era SFRT using predominantly a volumetric modulated arc therapy (VMAT) lattice technique.
View Article and Find Full Text PDFInt J Gen Med
December 2024
Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei 230031, People's Republic of China.
Purpose: To investigate risk factors for esophageal fistula in esophageal squamous cell cancer (ESCC) patients who treated with volumetric modulated arc therapy (VMAT).
Patients And Methods: A retrospective analysis was performed on 171 ESCC patients treated with VMAT at Hefei Cancer Hospital, Chinese Academy of Sciences, from February 2017 to February 2021. Clinical and dosimetric parameters, including age, gender, feeding channel, tumor location, T stage, ulcerative tumor, were recorded.
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