Numerous experimantal data show that melatonin secreted by the pineal gland and enterochromaffin cells (apudocites) of the gastrointestinal tract plays an universal protective role in cases of various disorders of the pancreatic gland. In experiments, this hormone restricts the manifestations of acute pancreatitis and diabetes mellitus. It is suggested that, after reliable clinical justification, melatonin can probably be used for therapeutic aims.
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