Purpose: To investigate the contribution ocular aberrations have on visual performance by quantifying improvements in best-corrected visual acuity (VA) and contrast sensitivity (CS) obtained with higher-order aberration (HOA) correction after penetrating (PK), deep anterior lamellar (DALK), or Descemet's stripping automated endothelial keratoplasty (DSAEK).

Methods: Sixteen eyes were evaluated from 14 subjects who underwent PK (n = 5), DALK (n = 6), or DSAEK (n = 5) greater than 1 year prior to study enrollment. Ocular aberrations were measured and an adaptive optics system was used to correct ocular lower-order aberration (LOA) and HOA. VA and CS were measured for each subject with LOA or full-aberration correction. CS was measured at each of three spatial frequencies: 4, 8, and 12 cycles/deg.

Results: All keratoplasty groups had more aberration than that of a normal myopic population and experienced significant VA gains with full-aberration correction (P < 0.0013). PK subjects had better VA than that of DSAEK subjects with LOA correction (logMAR VA 0.03 ± 0.05 vs. 0.25 ± 0.05; P = 0.0870). After HOA correction this trend persisted (P = 0.1734). DSAEK subjects also experienced less VA benefit from full-aberration correction than that of PK and DALK subjects. All keratoplasty groups demonstrated similar CS benefits from full-aberration correction despite differing higher-order root-mean-square magnitudes.

Conclusions: PK eyes had better logMAR VA than that of DSAEK eyes with LOA correction, whereas DALK eyes performed intermediate between the two. When full correction was applied, the same trend persisted. The findings suggest that factors other than aberration contribute to decrements in VA with DSAEK compared with PK.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558730PMC
http://dx.doi.org/10.1167/iovs.12-10003DOI Listing

Publication Analysis

Top Keywords

full-aberration correction
16
correction
10
visual performance
8
correction penetrating
8
penetrating deep
8
deep anterior
8
anterior lamellar
8
endothelial keratoplasty
8
ocular aberrations
8
hoa correction
8

Similar Publications

Achromatic doublet intraocular lens for full aberration correction.

Biomed Opt Express

May 2017

Instituto de Investigación en Óptica y Nanofísica, Laboratorio de Óptica, Universidad de Murcia, Edificio 34, Campus de Espinardo, 30100 Murcia, Spain.

A doublet intraocular lens optimized for both chromatic and monochromatic aberration correction in pseudophakic eyes is presented. Ray-tracing techniques were applied to design the lens in white light within a chromatic eye model. Combinations of two materials, already commonly used in intraocular lenses, as acrylic and silicone, were used.

View Article and Find Full Text PDF

Neural adaptation to peripheral blur in myopes and emmetropes.

Vision Res

March 2017

Flaum Eye Institute, University of Rochester, Rochester, NY, USA; Center for Visual Science, University of Rochester, Rochester, NY, USA; The Institute of Optics, University of Rochester, Rochester, NY, USA. Electronic address:

In the presence of optical blur at the fovea, blur adaptation can improve visual acuity (VA) and perceived image quality over time. However, little is known regarding blur adaptation in the peripheral retina. Here, we examined neural adaptation to myopic defocus at the fovea and parafovea (10° temporal retina) in both emmetropes and myopes.

View Article and Find Full Text PDF

Benefit of adaptive optics aberration correction at preferred retinal locus.

Optom Vis Sci

September 2012

Vision Enabling Laboratory, Section of Optometry and Vision Science, School of Natural Sciences, Linnaeus University, Kalmar, Sweden.

Purpose: To investigate the effect of eccentric refractive correction and full aberration correction on both high- and low-contrast grating resolution at the preferred retinal locus (PRL) of a single low-vision subject with a long-standing central scotoma.

Methods: The subject was a 68-year-old women with bilateral absolute central scotoma due to Stargardt disease. She developed a single PRL located 25° nasally of the damaged macula in her left eye, this being the better of the two eyes.

View Article and Find Full Text PDF

Purpose: To investigate the contribution ocular aberrations have on visual performance by quantifying improvements in best-corrected visual acuity (VA) and contrast sensitivity (CS) obtained with higher-order aberration (HOA) correction after penetrating (PK), deep anterior lamellar (DALK), or Descemet's stripping automated endothelial keratoplasty (DSAEK).

Methods: Sixteen eyes were evaluated from 14 subjects who underwent PK (n = 5), DALK (n = 6), or DSAEK (n = 5) greater than 1 year prior to study enrollment. Ocular aberrations were measured and an adaptive optics system was used to correct ocular lower-order aberration (LOA) and HOA.

View Article and Find Full Text PDF

An achromatizing lens has been designed for the human eye in the near infrared range, from 700 to 900 nm, for retinal imaging purposes. Analysis of the performance of the lens, including tolerance to misalignments, has been mathematically accomplished by using an existing eye model. The calculations have shown a virtually perfect correction of the ocular longitudinal chromatic aberration, while still keeping a high optical quality.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!