Aims: Alcohol misuse by young people causes significant health and social harm, including death and disability. Therefore, prevention of youth alcohol misuse is a policy aim in many countries. Our aim was to examine the effectiveness of (1) school-based, (2) family-based and (3) multi-component universal alcohol misuse prevention programmes in children and adolescents.
Methods: Three Cochrane systematic reviews were performed: searches in MEDLINE, EMBASE, PsycINFO, Project CORK and the Cochrane Register of Controlled Trials up to July 2010, including randomised trials evaluating universal alcohol misuse prevention programmes in school, family or multiple settings in youths aged 18 years or younger. Two independent reviewers identified eligible studies and any discrepancies were resolved via discussion.
Results: A total of 85 trials were included in the reviews of school (n = 53), family (n = 12) and multi-component (n = 20) programmes. Meta-analysis was not performed due to study heterogeneity. Most studies were conducted in North America. Risk of bias assessment revealed problems related to inappropriate unit of analysis, moderate to high attrition, selective outcome reporting and potential confounding. Certain generic psychosocial and life skills school-based programmes were effective in reducing alcohol use in youth. Most family-based programmes were effective. There was insufficient evidence to conclude that multiple interventions provided additional benefit over single interventions.
Conclusions: In these Cochrane reviews, some school, family or multi-component prevention programmes were shown to be effective in reducing alcohol misuse in youths. However, these results warrant a cautious interpretation, since bias and/or contextual factors may have affected the trial results. Further research should replicate the most promising studies identified in these reviews and pay particular attention to content and context factors through rigorous evaluation.
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http://dx.doi.org/10.1177/1757913912443487 | DOI Listing |
Ther Adv Drug Saf
January 2025
Pharmacology Department, School of Medicine, University of Valladolid, Valladolid, Spain.
In 2019, intranasal esketamine gained approval as a promising therapy for those individuals grappling with treatment-resistant depression. Both clinical trials and real-world studies have underscored its efficacy in alleviating and remitting depressive symptoms, with sustained benefits observed for nearly 4.5 years.
View Article and Find Full Text PDFScand J Prim Health Care
January 2025
Primary Health Care Centre Ekholmen, Linköping and Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
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Design, Participants, And Setting: Individual interviews were conducted with GPs and resident GPs (n 20) in Swedish PHC and analysed using qualitative content analysis.
Subst Use Misuse
January 2025
Psychological Sciences Department, Western Kentucky University, Bowling Green, KY, USA.
Background: Alcohol use among emerging adults is a public health concern, as it has been associated with numerous negative consequences. Poor sleep has repeatedly been associated with alcohol-related consequences in this age group, yet factors impacting this relationship and potential moderators remain largely unexplored.
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Subst Use Misuse
January 2025
Defense Personnel and Security Research Center, Peraton, Seaside, California, USA.
Background: This study investigated relationships between low-income adolescent drinkers' frequent alcohol use and five factors: social disorganization, social structural, social integration, mental health, and access to healthcare.
Objective: A sample of 1,256 low-income adolescent drinkers and caregivers were extracted from the Future of Families and Child Wellbeing Study.
Results: Logistic regression yielded results showing adolescent drinkers' weekly drinking to be associated positively with Hispanic adolescents, drinking peers, adolescents' depression/anxiety, and caregiver's daily drinking.
Int J Mol Sci
January 2025
Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Alcohol is the second-most misused substance after tobacco. It has been identified as a causal factor in more than 200 diseases and 5.3% of all deaths and is associated with significant behavioral, social, and economic difficulties.
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