It is well known that periconceptional folic acid supplementation decreases the risk of neural tube defects. The aim of this study was to evaluate the attitudes and practices of women with planned pregnancies regarding periconceptional folic acid intake and to identify factors associated with the use of this supplement. During 2 years of observation, we surveyed women with planned pregnancies who called our Teratology Information Service. A total of 500 women were surveyed: 217 (43.4%) took folic acid before becoming pregnant, and 283 (56.6%) did not take it. The women who took folic acid before becoming pregnant had a high education level and received preconception counselling. Our results suggest that less than half of Italian women took folic acid before they became pregnant although they were trying to conceive. Knowledge about the benefits of this vitamin is inadequate also among women who planned the pregnancy and the level of information received from their physicians.
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http://dx.doi.org/10.1007/s10995-012-1047-2 | DOI Listing |
ACS Omega
December 2024
Faculty of Chemistry, University of Warsaw, Warsaw 02-093, Poland.
Gold nanobowls (AuNBs) synthesized by the template-free method were deposited on graphene oxide (GO) to obtain an ultrasensitive surface enhanced Raman spectroscopy (SERS) platform for folic acid (FA) detection. GO was conditioned in aqueous solutions at various pH values to optimize the adsorption of the FA molecule and the intensity of the SERS signal. It was found that the conditioning procedure influences the orientation of FA on the SERS supports and the quality of the spectra in result.
View Article and Find Full Text PDFCurr Dev Nutr
December 2024
Department of Population, Family and Reproductive Health, School of Public Health, University of Ghana, Accra, Ghana.
Background: Early and delayed puberty are both associated with adverse health and psychosocial outcomes.
Objectives: We assessed the impact of provision of small-quantity lipid-based nutrient supplement (SQ-LNS) to mothers during pregnancy and 6 mo postpartum and to their children aged 6-18 mo, on pubertal status.
Methods: This study was a follow-up to a partially double-blind randomized controlled trial.
Yakugaku Zasshi
January 2025
Division of Drug Informatics, Keio University Faculty of Pharmacy.
Pemetrexed is a folate analog inhibitor for the treatment of non-small-cell lung cancer (NSCLC). Prophylactic supplementation with vitamin B and folic acid reduces hematotoxicity associated with pemetrexed. Metformin, the antidiabetic agent, has been associated with the potential side effect of vitamin B deficiency.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Floriculture, Ornamental Horticulture and Garden Design, Faculty of Agriculture (El-Shatby), Alexandria University, Alexandria, 21545, Egypt.
Natural extracts as biostimulants have the potential to enhance the productivity and growth of many medicinal and aromatic plants. This study aimed to enhance the growth, and essential oil (EO) content, as well as composition of Lavandula latifolia Medik. by using Malva parviflora L.
View Article and Find Full Text PDFDev Biol
January 2025
Department of Molecular, Cellular and Development Biology, University of Colorado, Boulder, CO 80309. Electronic address:
Folic acid (FA) supplementation is a potent tool to reduce devastating birth defects known as neural tube defects (NTDs). Though effective, questions remain how FA achieves its protective effect and which gene mutations are sensitive to folic acid levels. We explore the relationship between FA dosage and NTD rates using NTD mouse models.
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