Molecular and cellular effects of Auger emitters: 2008-2011.

Int J Radiat Biol

Department of Biological Sciences, Northern Illinois University, DeKalb, Illinois 60115, USA.

Published: December 2012

Purpose: To review recent Auger emitter research with an emphasis on a review of findings on targeting and accumulation of Auger emitters in tumor cells.

Conclusion: Significant progress can be reported for targeting methods and improvements in methods to accumulate Auger emitters in the target cells, as well as advances in dose calculations. These studies further our understanding of how Auger emitters induce cell death at a cellular and molecular level, supporting the targeted radiomedical applications of Auger emitters.

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http://dx.doi.org/10.3109/09553002.2012.702296DOI Listing

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