We report the case of a 36-year-old, drug-addicted woman with laboratory evidence of human immunodeficiency virus infection in the central nervous system. The patient presented with generalized dystonia involving both axial and segmental muscles, mainly in the legs, and with minimal additional neurological abnormalities. A computed-tomographic scan revealed bilateral and symmetrical lucencies in the putaminal region. The possibility of an acquired immunodeficiency syndrome-related manifestation is discussed.
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http://dx.doi.org/10.1159/000117377 | DOI Listing |
Epileptic Disord
March 2025
Department of Neurology, Neurological Institute, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.
Eur J Paediatr Neurol
March 2025
First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, "Agia Sophia" Children's Hospital, Thivon and Papadiamantopoulou, Athens, 11527, Greece. Electronic address:
Background: Developmental and epileptic encephalopathy (DEE) includes diseases where there is developmental impairment related to both the underlying etiology independent of epileptiform activity and the epileptic encephalopathy. Patients often present with movement disorders (MD). This study aims to delineate the motor phenotype in a cohort of patients with DEE.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Pediatric, Children Hospital, Taif, Saudi Arabia.
Manganese-induced neurological disorder (HMNDYT1) is a rare condition characterized by the accumulation of manganese in the brain, leading to neurological symptoms such as difficulties in walking. This disorder arises due to genetic mutations affecting manganese transport and metabolism. Presented is the case of a 5-year-9-month-old female from the south region, evaluated for walking difficulties.
View Article and Find Full Text PDFNeuropediatrics
March 2025
Department of Pediatric Neurology, Neurorehabilitation and Epileptology, Schoen Clinic Vogtareuth, Vogtareuth, Germany.
The spinal application of intrathecal baclofen (ITB) has been commonly used as treatment for severe dystonia as well spasticity. However, in rare cases, the use of ITB is not possible or ineffective. Therefore, intraventricular application of baclofen (IVB) mostly using endoscopic navigation has been rarely performed over the last years.
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