Background: Patients undergoing abdominal wall reconstruction are at risk of developing major postoperative respiratory complications. The authors attempted to identify factors predictive of respiratory complications following abdominal wall reconstruction.
Methods: All patients who underwent complex abdominal wall reconstruction over a 2-year period were reviewed. The primary endpoint studied was severe respiratory complication, defined as respiratory insufficiency requiring intubation or transfer to a higher level of care.
Results: Sixty patients underwent complex abdominal wall reconstruction during the study period. The incidence of respiratory complications was 20 percent. Factors predictive of postoperative respiratory complication included age (p = 0.05), American Society of Anesthesiologists score (p = 0.04), and hernia defect size (p = 0.01). In addition, patients who developed respiratory complications were more likely to have had a greater change in plateau pressure (5.8 versus 2.3 cmH(2)O; p = 0.01). The greater the change in plateau pressure, the greater the risk of developing a respiratory complication: for a change in plateau pressure greater than or equal to 6 cmH(2)O, the odds ratio was 8.67; for a change in plateau pressure greater than or equal to 9 cmH(2)O, the odds ratio was 11.5.
Conclusions: Respiratory complications following abdominal wall reconstruction can be serious and are associated with prolonged hospitalizations. Patients with an increase in their plateau pressure of greater than 6 cmH(2)O are at an increased risk of severe postoperative respiratory complications.
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http://dx.doi.org/10.1097/PRS.0b013e318262f160 | DOI Listing |
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with significant comorbidities, including cardiovascular and respiratory complications, leading to increased hospitalization rates in Intensive Care Units (ICUs) and Cardiac Intensive Care Units (CICUs). This study examines factors related to ICU/CICU admissions among Polish RA patients from 2011 to 2021.
Objectives: The study aims to analyze trends in ICU/CICU admissions, identify key factors influencing outcomes, and assess the impact of comorbidities on RA patient ICU/CICU mortality in critical care settings.
Tuberk Toraks
December 2024
Department of Medical Microbiology, Dokuz Eylül University Faculty of Medicine, İzmir, Türkiye.
Introduction: In solid-organ transplant (SOT) recipients, while survival rates have improved with immunosuppressive therapies, the risk of opportunistic infections has also increased. This study aimed to evaluate the frequency of pneumonia, identify microbiological factors, investigate diagnostic methods, and analyse prognosis.
Materials And Methods: A retrospective study was conducted to identify adult SOT recipients referred to the pulmonary diseases department with a preliminary pneumonia diagnosis between 2011 and 2019.
The risk of severe outcomes of influenza increases during pregnancy. Whether vaccine-induced T cell memory-primed prepregnancy retains the ability to mediate protection during pregnancy, when systemic levels of several hormones with putative immunomodulatory functions are increased, is unknown. Here, using murine adoptive transfer systems and a translationally relevant model of cold-adapted live-attenuated influenza A virus vaccination, we show that preexisting virus-specific memory T cell responses are largely unaltered and highly protective against heterotypic viral challenges during pregnancy.
View Article and Find Full Text PDFCureus
December 2024
Physical Medicine and Rehabilitation, Unidade Local de Saúde (ULS) de Viseu Dão-Lafões, Viseu, PRT.
Introduction: Dysphagia is a common post-stroke neurological disorder. Early screening for dysphagia can identify patients at risk of aspiration, thereby reducing the occurrence of pulmonary complications, morbidity, and mortality in this population.
Objectives: This study aims to evaluate the impact of an intervention in a stroke unit, following a retrospective study carried out in the same unit in 2020, which investigated the association between dysphagia and acute cerebrovascular disease and analyzed the prevalence of readmissions due to respiratory tract infections (RTI) and mortality.
World J Hepatol
December 2024
Center of Liver Diseases Division 3, Beijing Ditan Hospital, Capital Medical University, Peking University Ditan Teaching Hospital, Beijing 100015, China.
Background: The incidence of () infection in patients with cirrhosis has been increasing over recent years, posing certain difficulties in clinical treatment.
Aim: To analyze the clinical features of patients with liver cirrhosis and identify the risk factors to help the early diagnosis and treatment of these diseases.
Methods: Clinical data and laboratory tests were collected from 72 patients with cirrhosis confirmed by secretion or blood culture of infection at Beijing Ditan Hospital, Capital Medical University, between May 2016 and October 2018.
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