The authors report the incidental finding of a dilated cisterna magna with an abnormal configuration to the falx in a newborn infant with Marfan syndrome who was recruited to a research study involving whole body MRI. To our knowledge, dilation of the cisterna magna has not previously been reported in patients with Marfan syndrome. Potential implications for antenatal diagnosis, the ethics of recruiting healthy volunteers for research and directions for future work are discussed.
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http://dx.doi.org/10.1136/bcr.06.2011.4328 | DOI Listing |
Life (Basel)
January 2025
Unit of Maternal-Fetal-Medicine, Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, GR-68100 Alexandroupoli, Greece.
Gestational diabetes mellitus (GDM) is a prevalent medical complication in pregnancy that is rapidly escalating worldwide, with epidemic implications. This systematic review aims to identify fetal brain changes using neurosonography and pinpoint potential markers for the early diagnosis of GDM. We conducted a literature search from 6 January 2013 to 4 September 2024 to identify studies examining fetal brain development using ultrasound in pregnancies affected by GDM compared to uncomplicated pregnancies.
View Article and Find Full Text PDFJ Cereb Blood Flow Metab
February 2025
Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri, 63130, USA.
The glymphatic system regulates cerebrospinal fluid (CSF) transport and brain waste clearance. Focused ultrasound combined with microbubbles (FUSMB) has shown feasibility for manipulating glymphatic transport, yet its mechanisms remain poorly understood. In this work, we used in vivo two-photon microscopy to reveal how FUSMB manipulates the CSF tracer transport in the mouse brain.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Maternal and Fetal Medicine, General Campus Ottawa Hospital, Ottawa, Canada.
Background: Fetal dural venous sinus thrombosis is an uncommon disorder in which a blood clot forms in the developing fetus's dural venous sinuses. A detailed ultrasound examination, including neurosonography, and color Doppler are usually used to identify it, and fetal brain magnetic resonance imaging (MRI) is used to confirm the diagnosis. Although few case reports exist, the incidence of fetal occurrence remains unknown.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
February 2025
Post-graduation Program in Health Sciences from IAMSPE-São Paulo-Brazil.
Study Design: A comprehensive search was conducted in PubMed/EMBASE/MEDLINE databases. Inclusion criteria included publications between January 2011 and December 2022 on CM diagnosis classification, natural history, and conservative management.
Objective: This study aims to offer an update on diagnosis classifications, natural history, and conservative management in Chiari Malformation (CM).
bioRxiv
January 2025
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.
Tracer imaging has been instrumental in mapping the brain's solute transport pathways facilitated by cerebrospinal fluid (CSF) flow. However, the impact of tracer infusion parameters on CSF flow remains incompletely understood. This study evaluated the influence of infusion location, rate, and anesthetic regimens on tracer transport using dynamic contrast-enhanced MRI with Gd-DTPA as a CSF tracer.
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