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Micromodification in bulk undoped polymethylmethacrylate (PMMA) by single focused (numerical aperture (NA) = 0.25), 1030-nm 250-fs laser pump pulses was explored by pump self-transmittance; optical, 3D-scanning confocal photoluminescence (PL); Raman micro-spectroscopy; and optical polarimetric and interferometric microscopy. Starting from the threshold pulse energy = 0.
View Article and Find Full Text PDFImproved konjac glucomannan/curdlan-based emulsion coating by mung bean protein addition for cherry tomato preservation.
Int J Biol Macromol
December 2024
National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, Wuhan 430068, China; Faculty of Engineering, University of Nottingham, Nottingham NG7 2RD, UK. Electronic address:
Biopolymer-based emulsion systems have been used for food preservation. In this study, mung bean protein (MBP) was added to konjac glucomannan (KGM)/curdlan-based camellia oil emulsion (KC-CO) to develop KCM-CO emulsion system. KCM-CO emulsions showed good compatibility and stability during storage.
View Article and Find Full Text PDFThe Mitochondrial Lactate Oxidation Complex: endpoint for carbohydrate carbon disposal.
Am J Physiol Endocrinol Metab
December 2024
Exercise Physiology Laboratory, Department of Integrative Biology, University of California, Berkeley, CA 94720-3140.
The Lactate Shuttle concept has revolutionized our understanding and study of metabolism in physiology, biochemistry, metabolism, nutrition, and medicine. Seminal findings of the Mitochondrial Lactate Oxidation Complex (mLOC) elucidated the architectural structure of its components. Here, we report that the mitochondrial pyruvate carrier (mPC) is an additional member of the mLOC in mouse muscle and C2C12 myoblasts and myotubes.
View Article and Find Full Text PDFPolarization and Characterization of M1 and M2 Human Monocyte-Derived Macrophages on Implant Surfaces.
J Vis Exp
December 2024
Department of Medical Materials Science & Technology, Institute for Biomedical Engineering, University Hospital Tübingen;
Foreign body reaction (FBR), an immune-mediated complex healing process, plays a crucial role in integrating implants into the body. Macrophages, as the first line of immune system interaction with implant surfaces, play a bidirectional role in modulating the inflammation-regeneration balance. For a deep understanding and the evaluation of the reactions between implant materials and immune responses, reliable in vitro methods and protocols are pivotal.
View Article and Find Full Text PDFGOLPH3-STIP1 Complex Activates STAT3 Through Exosome Secretion to Induce Colon Cancer Metastasis.
Biotechnol J
December 2024
Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
With a high mortality rate, colon cancer (CC) is the third most common malignant tumor worldwide. The primary causes are thought to be the high invasiveness and migration of CC cells. The functions of Golgi phosphoprotein 3 (GOLPH3), stress-induced phosphoprotein 1 (STIP1), and the signal transducer and activator of transcription 3 (STAT3) signaling pathway in the invasion and migration of CC cells were examined in this study.
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