AI Article Synopsis
- The development of point-of-care (POC) testing technology is advancing rapidly, producing smaller and more reliable instruments for health analysis.
- POC tests often focus on proteins through immunoassays to detect markers related to tumors, inflammation, and heart conditions, but other methods for analyzing plasma proteins also exist.
- Nucleic acid testing uses hybridization and amplification techniques to identify infections and cancers, with a focus on newer technologies like lab-on-a-chip that promise miniaturization for future applications.
Article Abstract
The field of point-of-care (POC) testing technology is developing quickly and producing instruments that are increasingly reliable, while their size is being gradually reduced. Proteins are a common target for POC analyses and the detection of protein markers typically involves immunoassays aimed at detecting different groups of proteins such as tumor markers, inflammation proteins, and cardiac markers; but other techniques can also be used to analyze plasma proteins. In the case of nucleic acids, hybridization and amplification strategies can be used to record electromagnetic or electric signals. These techniques allow for the identification of specific viral or bacterial infections as well as specific cancers. In this review, we consider some of the latest advances in the analysis of specific nucleic acid and protein biomarkers, taking into account their trend toward miniaturization and paying special attention to the technology that can be implemented in future applications, such as lab-on-a-chip instruments.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104926 | PMC |
| http://dx.doi.org/10.1016/j.trsl.2012.02.012 | DOI Listing |
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