A series of 5-alkylaminolquinolines was designed and synthesized as potential novel CRF(1) receptor antagonists. The structure-activity relationships (SARs) of the substituents on each position (R(2), R(3), R(5) and R(5')) were investigated.
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| http://dx.doi.org/10.1016/j.bmcl.2012.05.066 | DOI Listing |
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