AI Article Synopsis
- Sleep apnoea syndrome (SAS) occurs in 40-80% of patients with acromegaly, prompting a study to examine its prevalence and relationship to acromegalic characteristics and comorbidities.
- In a cohort of 106 acromegalic patients, 42 were diagnosed with SAS, primarily severe cases, and this condition was linked to factors like older age, hypertension, and diabetes, but not to the control of acromegaly.
- The prevalence of SAS in acromegalic patients is significantly higher than in the general population, suggesting that routine screening for SAS in these patients may be necessary due to their increased risk.
Article Abstract
Introduction: Sleep apnoea syndrome (SAS) has a prevalence of between 40 and 80 % in patients with acromegaly. The objective of our study was to focus on the occurrence of SAS and its relation with acromegalic characteristics in this population as well as to study patients' comorbidities.
Methodology: This study was retrospective, monocentric and related to a cohort of 106 acromegalic patients of whom 55 patients had performed ventilatory polygraphic recordings looking for SAS in addition to assessment of comorbidities.
Results: Within the screened patients, 42 had sleep apnoea syndrome with a majority of them having severe SAS. In this population, SAS was associated with hypertension, diabetes and a longer duration of acromegaly but acromegaly control was not a risk factor. Patients with severe SAS were older (mean 64 years) than the ones without SAS (47 years) (P=0.01).
Conclusion: SAS prevalence is twenty times higher in the acromegalic population than for the normal population, even more so if patients are diabetic, hypertensive, older and if acromegaly has had a long evolution. Knowing this high prevalence, systematic screening for SAS may be justified in this population.
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| http://dx.doi.org/10.1016/j.rmr.2011.11.017 | DOI Listing |
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