Purpose: To compare the sensitivity, specificity, and interpretability of a newly developed semiautomated static perimeter based on the preferential looking response to the results of confrontation visual field testing in a group of young and/or developmentally delayed children with and without visual field deficit.
Methods: The preferential looking perimeter (PLP) uses observation of the child's natural eye movement response to an appearing target to determine the peripheral visual field. We compared preferential looking perimetry to confrontation testing in 74 children 3-10 years of age (mean, 6.6 years; median, 7 years), including 32 controls and 42 children with neurological and ocular disorders that could cause significant visual field deficit.
Results: Using confrontation testing as the gold standard, the PLP was 100% sensitive and 100% specific (95% CI, 90%-100%), with excellent interobserver agreement. An interpretable result could be achieved in 15 (71%) of the 21 children in whom confrontation testing was unhelpful.
Conclusions: PLP is a useful new technique for assessing significant visual field loss in young or developmentally delayed children, with many advantages over confrontation testing.
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http://dx.doi.org/10.1016/j.jaapos.2012.01.006 | DOI Listing |
Am Fam Physician
January 2025
Western University Schulich School of Medicine and Dentistry, London, Ontario, Canada.
Vision loss affects more than 7 million Americans and impacts quality of life, independence, social functioning, and overall health. Common and dangerous conditions causing sudden vision loss include acute angle-closure glaucoma, retinal detachment, retinal artery occlusion, giant cell arteritis, and optic neuritis. Acute angle-closure glaucoma features ocular pain, headache, and nausea; treatment includes pilocarpine eye drops, oral or intravenous acetazolamide, and intravenous mannitol.
View Article and Find Full Text PDFPLoS One
January 2025
School of Optometry and Vision Science, UNSW Sydney, Sydney, New South Wales, Australia.
Purpose: In this study, we investigated the performance of deep learning (DL) models to differentiate between normal and glaucomatous visual fields (VFs) and classify glaucoma from early to the advanced stage to observe if the DL model can stage glaucoma as Mills criteria using only the pattern deviation (PD) plots. The DL model results were compared with a machine learning (ML) classifier trained on conventional VF parameters.
Methods: A total of 265 PD plots and 265 numerical datasets of Humphrey 24-2 VF images were collected from 119 normal and 146 glaucomatous eyes to train the DL models to classify the images into four groups: normal, early glaucoma, moderate glaucoma, and advanced glaucoma.
Forensic Sci Res
December 2024
National Forensic Laboratory, Ljubljana, Slovenia.
Like other pattern recognition disciplines, forensic handwriting examination relies on various human factors. Expert opinions in the field are based on visual analysis and comparison, and the evaluation of findings is generally conducted without reference to tabulated data. This high level of subjectivity may contribute to bias and error in the examination process.
View Article and Find Full Text PDFOphthalmic Physiol Opt
January 2025
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Purpose: To investigate the repeatability of optical coherence tomography angiography (OCTA) parameters in participants with different severities of glaucoma.
Methods: Subjects with open-angle glaucoma were enrolled prospectively and categorised into mild (mean deviation [MD] of 24-2 visual field test ≥ -6 dB), moderate to advanced (-6 > MD ≥ -20 dB) and severe glaucoma groups (MD < -20 dB). OCTA was performed three times within a single visit to obtain superficial and deep macular vessel density (VD) and peripapillary vessel and capillary density.
Mikrochim Acta
January 2025
Department of Biotechnology and Bioengineering, Chonnam National University, Gwangju, 61186, Republic of Korea.
The global healthcare market increasingly demands affordable molecular diagnostics for field testing. To address this need, we introduce a lab-on-paper (LOP) platform that integrates isothermal amplification with a specially designed paper strip for molecular testing through an automated microfluidics process. The LOP system is engineered for rapid, cost-effective, and highly sensitive detection, using USB-powered thermal management and a wax valve mechanism.
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