TGF-β drives DNA demethylation.

Mol Cell

Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, VA 22908, USA.

Published: June 2012

In this issue of Molecular Cell, Thillainadesan et al. (2012) provide evidence that Smad proteins promote locus-specific active DNA demethylation as part of the transforming growth factor β (TGF-β) transcriptional response.

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Source
http://dx.doi.org/10.1016/j.molcel.2012.05.031DOI Listing

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